Selank 5mg

$34.95

Selank, a synthetic tuftsin-derived heptapeptide (TKPRPGP), supplied for neuropeptide and gene-expression research models.
Batch Certification
COA pending
The third-party certificate of analysis for this lot will be posted on our Lab Results page before release.
Specifications
CAS Number: 129954-34-3
Form: Lyophilized Powder
Quantity: 5mg per vial
Purity: Pending (lot COA in progress)
Molecular Formula: C₃₃H₅₇N₁₁O₉
Molecular Weight: 751.9 g/mol (free base)
Storage: −20°C recommended
Stability: Listed on lot COA
Research Category: Neuropeptide Research
Use: Not for human or animal use. Research laboratory use only.

Selank, a synthetic tuftsin-derived heptapeptide (TKPRPGP), supplied for neuropeptide and gene-expression research models.

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Product Overview

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built on tuftsin, an endogenous tetrapeptide (Thr-Lys-Pro-Arg) derived from the Fc region of immunoglobulin G. The C-terminal Pro-Gly-Pro extension was added to the tuftsin core to slow enzymatic breakdown, which is why Selank is studied as a more stable tuftsin analog. It is used in laboratory settings to study regulatory peptides, neuropeptide signaling and peptide-driven changes in gene expression.

  • Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
  • Molecular formula: C33H57N11O9 (free base)
  • Molecular weight: 751.9 g/mol (free base)
  • CAS: 129954-34-3

Specifications: lyophilized powder · 5 mg per vial · purity and salt form confirmed on the lot-specific certificate of analysis, published on our Lab Results page when the lot is released · store at −20 °C, protected from light and moisture.

Frequently asked questions

What form is Selank supplied in?
A lyophilized (freeze-dried) powder in a sealed 5 mg vial. Salt form, purity and identity data are listed on the certificate of analysis for each lot.

How should the vial be stored?
Keep the sealed vial at −20 °C, away from light and moisture, until use.

Is this product for human or veterinary use?
No. It is sold strictly for in vitro and laboratory research. Not for human or animal use.

All compounds referenced are supplied for laboratory and research applications only and are not for human consumption.

Selank belongs to a family of synthetic peptides designed by extending a short natural regulatory peptide with a Pro-Gly-Pro tail to improve stability. Its parent sequence, tuftsin, has a long history in immunology research, and Selank has been examined for whether it keeps some of that immunomodulatory character. In mouse spleen, researchers measured the expression of inflammation-related genes after Selank administration and reported shifts in a defined subset of them.1

A second line of work looks at the nervous system. Using rat frontal cortex tissue, investigators profiled genes involved in GABAergic neurotransmission and reported that Selank administration changed the expression of several of them, which has made the peptide a reference tool in studies of GABA-related signaling at the transcript level.2

Not for human or animal use. Research laboratory use only.

References

  1. Kolomin T, Shadrina M, Andreeva L, et al. Regul Pept. 2011;170(1-3):18-23. PMID: 21609736. PubMed
  2. Volkova A, Shadrina M, Kolomin T, et al. Front Pharmacol. 2016;7:31. PMID: 26924987. PubMed
For laboratory research use only. Not for human or veterinary consumption.

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