GLP-2 10mg/20mg

Price range: $75.00 through $95.00

Specifications
CAS Number: 2023788-19-2
Form: Lyophilized Powder
Quantity: 10mg / 20mg
Purity: ≥99% (HPLC verified)
Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
Molecular Weight: 4,813.45 g/mol
Storage: −20°C recommended
Stability: 24+ months lyophilized
Research Category: Advanced GLP Research Compound
Use: Research purposes only — not for human or veterinary use

CAS Number: 2023788-19-2
Form: Lyophilized Powder
Quantity: 10mg / 20mg
Purity: ≥99% (HPLC verified)
Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
Molecular Weight: 4,813.45 g/mol
Storage: −20°C recommended
Stability: 24+ months lyophilized
Category: Advanced GLP Research Compound
Use: Research purposes only — not for human or veterinary use

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Product Overview

GLP-2 is a research peptide of the dual glucose-dependent insulinotropic polypeptide (GIP) / glucagon-like peptide-1 (GLP-1) receptor agonist class, supplied exclusively for in vitro and preclinical laboratory investigation. It is defined within the peptide research community by its capacity to engage two distinct incretin receptor systems, and is studied in research on incretin receptor signaling and metabolic-pathway biology. GLP-2 is offered as a reference material for mechanistic studies examining co-activation of the GIP and GLP-1 receptors and their downstream signal transduction. All handling, storage, and experimental use are intended strictly for qualified research personnel operating in a controlled laboratory setting. No representation is made regarding any clinical or diagnostic application.

Not for human or animal use. Research laboratory use only.

All compounds referenced are supplied for laboratory and research applications only and are not for human consumption.

GLP-2 is classified as a dual GIP / GLP-1 receptor agonist research peptide, a structural category defined by its capacity to engage two distinct incretin receptor systems. The incretin axis has been characterized as a principal regulator of nutrient-dependent endocrine signaling, and comparative studies of GIP and GLP-1 have been undertaken to delineate the overlapping and divergent properties of their receptors.1 GLP-1 receptor biology has been investigated for its role in G-protein-coupled receptor activation and cAMP-dependent intracellular signaling across cell-based and preclinical model systems.2 Foundational reviews of incretin pharmacology have examined receptor distribution, ligand binding, and signal transduction within the GIP and GLP-1 receptor families,3 providing the mechanistic framework in which dual-agonist research peptides are studied. GLP-2 is used as a reference material in research on co-agonism, where simultaneous occupancy of the GIP and GLP-1 receptors is examined at the level of receptor conformation, downstream kinase cascades, and receptor internalization.4 Within this framework, GLP-2 has been of interest to investigators studying incretin receptor signaling and metabolic-pathway biology in controlled experimental settings. It is characterized strictly as a laboratory reagent for mechanistic and receptor-pharmacology research; nothing presented here describes or implies any clinical or diagnostic use.

Not for human or animal use. Research laboratory use only.

References

  1. Campbell JE, Drucker DJ. 2013;17(6):819-837. PMID: 23684623. https://pubmed.ncbi.nlm.nih.gov/23684623/
  2. Drucker DJ. 2018;27(4):740-756. PMID: 29617641. https://pubmed.ncbi.nlm.nih.gov/29617641/
  3. Baggio LL, Drucker DJ. 2007;132(6):2131-2157. PMID: 17498508. https://pubmed.ncbi.nlm.nih.gov/17498508/
  4. Muller TD, Finan B, Bloom SR, et al. 2019;30:72-130. PMID: 31767182; PMCID: PMC6812410. https://pmc.ncbi.nlm.nih.gov/articles/PMC6812410/

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For laboratory research use only. Not for human or veterinary consumption.

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